Given the importance of self-employment for economic growth and integration, clarification of the interrelationships between potential factors underlying the disposition to be self-employed is essential. Using the family as nexus, this project is innovative as it aims to combine different models of explanation for self-employment using quantitative data. Our primary research question is: How much does the family affect the propensity of self-employment? Our aim is also to examine whether certain groups of individuals (individuals from specific countries of birth, individuals residing in specific areas and individuals working in specific branches of the labor market) are more or less susceptible than others to family environment. However, it is very unlikely that self-employment is determined solely by environmental factors; therefore our subsequent endeavor is to disentangle the proposed family effect on self-employment into shared familial environmental, unique individual environmental and genetic effects.